Author: Bahir, Iris; Fromer, Menachem; Prat, Yosef; Linial, Michal
Title: Viral adaptation to host: a proteome-based analysis of codon usage and amino acid preferences Document date: 2009_10_13
ID: 629kl04a_50
Snippet: In multicellular organisms, viruses do not infect the organism but rather are restricted to a specific organ, tissue, or cell type (Gallagher and Buchmeier, 2001) . Throughout this study, we presented data that use the average codon usage of the organism as a reference measure to study adaptation. With the fast growth of high-quality mass spectrometry proteomics data from different tissues and cell types, the notion of resemblance between viruses.....
Document: In multicellular organisms, viruses do not infect the organism but rather are restricted to a specific organ, tissue, or cell type (Gallagher and Buchmeier, 2001) . Throughout this study, we presented data that use the average codon usage of the organism as a reference measure to study adaptation. With the fast growth of high-quality mass spectrometry proteomics data from different tissues and cell types, the notion of resemblance between viruses and their hosts under the assumption of translational (and not transcriptional) efficiency at the tissue and cell-type levels will be of great interest.
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