Author: Munday, Diane C.; Emmott, Edward; Surtees, Rebecca; Lardeau, Charles-Hugues; Wu, Weining; Duprex, W. Paul; Dove, Brian K.; Barr, John N.; Hiscox, Julian A.
Title: Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus Document date: 2010_7_20
ID: 2zhaknbi_52
Snippet: Network Pathway Analysis-IPA was used to analyze the data sets, investigate potential changes in specific cellular functions, and generate a priority list of proteins and pathways of interest. IPA identified several different biological pathways, some of which may be common to viral infection. For example, in common with the data gathered for HRSVinfected A549 cells, a proteomic analysis of the CD4 Ï© CEMx174 cell line infected with HIV-1 highlig.....
Document: Network Pathway Analysis-IPA was used to analyze the data sets, investigate potential changes in specific cellular functions, and generate a priority list of proteins and pathways of interest. IPA identified several different biological pathways, some of which may be common to viral infection. For example, in common with the data gathered for HRSVinfected A549 cells, a proteomic analysis of the CD4 Ï© CEMx174 cell line infected with HIV-1 highlighted changes in the carrier proteins in nucleocytoplasmic trafficking, cyclindependent kinases, and ubiquitination (77) . The latter process has also been identified in proteomic analysis of cells infected with avian infectious bursal disease virus (78) .
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