Selected article for: "limited number and RNA structure"
Author: Tuplin, A.; Evans, D. J.; Buckley, A.; Jones, I. M.; Gould, E. A.; Gritsun, T. S.
Title: Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus
  • Document date: 2011_5_27
    • ID: 0aiaklrn_21
    Snippet: Previous in silico studies have predicted a stable RNA structure designated SL6, in the C protein-encoding region, for a limited number of viruses within the mTBFV subgroup (16, (26) (27) (28) . Structural RNA elements were also revealed in the C region of some MBFV (28) although their homology to SL6 of TBFV had not been established. Here, we utilized a variety of independent structure prediction methods and a much larger sample of viral sequenc.....
    Document: Previous in silico studies have predicted a stable RNA structure designated SL6, in the C protein-encoding region, for a limited number of viruses within the mTBFV subgroup (16, (26) (27) (28) . Structural RNA elements were also revealed in the C region of some MBFV (28) although their homology to SL6 of TBFV had not been established. Here, we utilized a variety of independent structure prediction methods and a much larger sample of viral sequences to analyze whether or not the SL6-like structure was conserved throughout the entire genus Flavivirus.

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