Selected article for: "apoptotic cell and cell body"
Author: Dong, Xiaoxv; Ni, Boran; Fu, Jing; Yin, Xingbin; You, Longtai; Leng, Xin; Liang, Xiao; Ni, Jian
Title: Emodin induces apoptosis in human hepatocellular carcinoma HepaRG cells via the mitochondrial caspase-dependent pathway
  • Document date: 2018_8_2
    • ID: 02r8i5n1_27
    Snippet: Compared with the control treatment, emodin significantly decreased the viability of HepaRG cells in a dose and time-dependent manner. DAPI and Annexin V/PI double staining further confirmed that emodin inhibited the growth of HepaRG cells in a dose-dependent manner via apoptosis, as confirmed by cell shrinkage, apoptotic body formation and DNA fragmentation. Thus, the results showed that the cytotoxic effect on HepaRG cells induced by emodin was.....
    Document: Compared with the control treatment, emodin significantly decreased the viability of HepaRG cells in a dose and time-dependent manner. DAPI and Annexin V/PI double staining further confirmed that emodin inhibited the growth of HepaRG cells in a dose-dependent manner via apoptosis, as confirmed by cell shrinkage, apoptotic body formation and DNA fragmentation. Thus, the results showed that the cytotoxic effect on HepaRG cells induced by emodin was attributed to apoptosis.

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