Author: Srivastava, Sukrit; Kamthania, Mohit; Singh, Soni; Saxena, Ajay K; Sharma, Nishi
Title: Structural basis of development of multi-epitope vaccine against Middle East respiratory syndrome using in silico approach Document date: 2018_11_21
ID: 33h22ikl_40
Snippet: sequence-based B-cell epitope prediction Initially, a total of 144 B-cell epitopes were screened from 13 MERS-CoV proteins, with epitope length of four or more than four amino acids by the BepiPred Linear Epitope Prediction method. The epitopes predicted by five other methods based on different physicochemical properties showed a significant consensus overlap of amino acid sequences with that of BepiPred Linear Epitope Prediction. From the 144 B-.....
Document: sequence-based B-cell epitope prediction Initially, a total of 144 B-cell epitopes were screened from 13 MERS-CoV proteins, with epitope length of four or more than four amino acids by the BepiPred Linear Epitope Prediction method. The epitopes predicted by five other methods based on different physicochemical properties showed a significant consensus overlap of amino acid sequences with that of BepiPred Linear Epitope Prediction. From the 144 B-cell epitopes, 12 with the length of 4-19 amino acids were shortlisted (Table S8 and Figure 2 ).
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