Author: Sztuba-Solinska, Joanna; Teramoto, Tadahisa; Rausch, Jason W.; Shapiro, Bruce A.; Padmanabhan, Radhakrishnan; Le Grice, Stuart F. J.
Title: Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome Document date: 2013_3_26
ID: 1pbd4maf_38
Snippet: Collectively, chemical probing analysis of DENV-MINI mutants supported the notion that, rather then being involved in the TL2/PK1 pseudoknot interaction, the structure-and sequence-specific composition of the PK1 region is essential for sustaining the correct conformation of the 5 0 and 3 0 terminal motifs necessary for 5 0 -3 0 terminal RNA-RNA interaction......
Document: Collectively, chemical probing analysis of DENV-MINI mutants supported the notion that, rather then being involved in the TL2/PK1 pseudoknot interaction, the structure-and sequence-specific composition of the PK1 region is essential for sustaining the correct conformation of the 5 0 and 3 0 terminal motifs necessary for 5 0 -3 0 terminal RNA-RNA interaction.
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