Author: Baek, Hyekyung; Kim, Kwang Ho; Park, Min Young; Kim, Kyeongryun; Ko, Bokyeong; Seo, Hyung Seok; Kim, Byoung Soo; Hahn, Tae-Wook; Yi, Sun Shin
Title: Establishment of minimal positive-control conditions to ensure brain safety during rapid development of emergency vaccines Document date: 2017_8_22
ID: 52sbckm3_31
Snippet: Meanwhile, in the developed protocol, very low levels of EB dye were detected in the brain parenchyma of B6/PBS and ICR/PBS mice (i.e., no LPS injected). Because EB dye has toxicity when injected in the body at a high concentration, it could slightly damage the BBB during circulation through the bloodstream [16, 17] ......
Document: Meanwhile, in the developed protocol, very low levels of EB dye were detected in the brain parenchyma of B6/PBS and ICR/PBS mice (i.e., no LPS injected). Because EB dye has toxicity when injected in the body at a high concentration, it could slightly damage the BBB during circulation through the bloodstream [16, 17] .
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