Selected article for: "best fit substitution model and substitution model"

Author: MYRRHA, Luciana Wanderley; SILVA, Fernanda Miquelitto Figueira; VIDIGAL, Pedro Marcus Pereira; RESENDE, Maurício; BRESSAN, Gustavo Costa; FIETTO, Juliana Lopes Rangel; SANTOS, Marcus Rebouças; SILVA, Laura Morais Nascimento; ASSAO, Viviane Sisdelli; SILVA-JÚNIOR, Abelardo; de ALMEIDA, Márcia Rogéria
Title: Feline coronavirus isolates from a part of Brazil: insights into molecular epidemiology and phylogeny inferred from the 7b gene
  • Document date: 2019_8_23
  • ID: 1s25r3o0_24
    Snippet: Substitution rates also provide good insight into virus evolution, reflecting the restrictions in genetic diversity that lead to variations in adaptability and pathogenicity of the viral population [6] . Bayes factors analysis suggested that the Bayesian-relaxed exponential molecular clock was the best-fit model for the 7b gene sequences, and the estimated mean substitution rate was 5.686 × 10 −4 substitutions/site/year. This estimate agrees w.....
    Document: Substitution rates also provide good insight into virus evolution, reflecting the restrictions in genetic diversity that lead to variations in adaptability and pathogenicity of the viral population [6] . Bayes factors analysis suggested that the Bayesian-relaxed exponential molecular clock was the best-fit model for the 7b gene sequences, and the estimated mean substitution rate was 5.686 × 10 −4 substitutions/site/year. This estimate agrees with what has been described for other RNA viruses, whose rates generally range from 10 −2 to 10 −5 substitutions/site/year [9, 13, 26] .

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