Selected article for: "gel electrophoresis and heat shock"
Author: Munday, Diane C.; Emmott, Edward; Surtees, Rebecca; Lardeau, Charles-Hugues; Wu, Weining; Duprex, W. Paul; Dove, Brian K.; Barr, John N.; Hiscox, Julian A.
Title: Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus
  • Document date: 2010_7_20
    • ID: 2zhaknbi_4
    Snippet: A number of selected cellular pathways have been shown to change in HRSV-infected cells in culture and in vivo. Proteomics has been applied in several instances to the study of the interaction between HRSV and the host cell nuclear proteome (26) . In this study, nuclear extracts from uninfected and infected cells were analyzed using two-dimensional gel electrophoresis (2DE) coupled to MALDI-TOF MS. 24 proteins whose abundance altered by Ϯ2-fold .....
    Document: A number of selected cellular pathways have been shown to change in HRSV-infected cells in culture and in vivo. Proteomics has been applied in several instances to the study of the interaction between HRSV and the host cell nuclear proteome (26) . In this study, nuclear extracts from uninfected and infected cells were analyzed using two-dimensional gel electrophoresis (2DE) coupled to MALDI-TOF MS. 24 proteins whose abundance altered by Ϯ2-fold were identified and included heat shock proteins, oxidant-antioxidant enzymes, and proteins associated with nuclear domain 10 structures (ND10), which are also known as promyelocytic leukemia (PML) bodies (26) . More recently, 2DE was used to compare the potential effect of several different negative strand RNA viruses, including HRSV, parainfluenza virus, human metap-neumovirus, measles virus, and influenza virus, on the host cell proteome with common changes in proteins involved with apoptosis and endoplasmic reticulum stress being highlighted (27) .

    Search related documents:
    Co phrase search for related documents
    • cellular pathway and gel electrophoresis: 1, 2
    • cellular pathway and heat shock protein: 1
    • cellular pathway and host cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
    • cellular pathway and influenza virus: 1, 2, 3, 4
    • cellular pathway and measles virus: 1
    • common change and influenza virus: 1
    • dimensional gel electrophoresis and gel electrophoresis: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • dimensional gel electrophoresis and heat shock protein: 1, 2, 3, 4
    • dimensional gel electrophoresis and host cell: 1, 2, 3, 4, 5, 6
    • dimensional gel electrophoresis and influenza virus: 1
    • dimensional gel electrophoresis and measles virus: 1
    • endoplasmic apoptosis and gel electrophoresis: 1
    • endoplasmic apoptosis and host cell: 1, 2, 3, 4, 5
    • endoplasmic apoptosis and influenza virus: 1
    • gel electrophoresis and heat shock protein: 1, 2, 3, 4, 5
    • gel electrophoresis and host cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
    • gel electrophoresis and infected uninfected cell: 1
    • gel electrophoresis and influenza virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
    • gel electrophoresis and measles virus: 1, 2