Author: Hollien, Julie; Lin, Jonathan H.; Li, Han; Stevens, Nicole; Walter, Peter; Weissman, Jonathan S.
Title: Regulated Ire1-dependent decay of messenger RNAs in mammalian cells Document date: 2009_8_10
ID: 3gwm1c2f_11
Snippet: Because the parent Ire1 / cell line lacks Ire1 activity, we could probe specific functions of Ire1 by inserting variants of hIre1 targets tested were down-regulated in response to these three forms of ER stress in an Ire1-dependent manner (Fig. 1 , A-C)......
Document: Because the parent Ire1 / cell line lacks Ire1 activity, we could probe specific functions of Ire1 by inserting variants of hIre1 targets tested were down-regulated in response to these three forms of ER stress in an Ire1-dependent manner (Fig. 1 , A-C).
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