Author: Mohammadzadeh, Sara; Khabiri, Alireza; Roohvand, Farzin; Memarnejadian, Arash; Salmanian, Ali Hatef; Ajdary, Soheila; Ehsani, Parastoo
Title: Enhanced-Transient Expression of Hepatitis C Virus Core Protein in Nicotiana tabacum, a Protein With Potential Clinical Applications Document date: 2014_11_24
ID: 3posyr5n_38
Snippet: Although these ending results were consistent with the prior two reports on appropriate antigenicity of tobaccoderived HCVcp, both of those previous studies addressed only transgenic (stable) tobacco-plant generations for HCVcp (21, 22) . However, transient expression in plants is currently the method of choice due to the simplicity and feasibility of rapid protein expression, omitting tissue culture and regeneration costs, and ease of large scal.....
Document: Although these ending results were consistent with the prior two reports on appropriate antigenicity of tobaccoderived HCVcp, both of those previous studies addressed only transgenic (stable) tobacco-plant generations for HCVcp (21, 22) . However, transient expression in plants is currently the method of choice due to the simplicity and feasibility of rapid protein expression, omitting tissue culture and regeneration costs, and ease of large scale industrial plans growth (23) (24) (25) . While transgenic (stable) plant generation needs longer periods of transgenic production and more deleterious effects on gene silencing (21) which is not encountered in transient-expression approach (59) .
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