Author: Blazejewski, Tomasz; Nursimulu, Nirvana; Pszenny, Viviana; Dangoudoubiyam, Sriveny; Namasivayam, Sivaranjani; Chiasson, Melissa A.; Chessman, Kyle; Tonkin, Michelle; Swapna, Lakshmipuram S.; Hung, Stacy S.; Bridgers, Joshua; Ricklefs, Stacy M.; Boulanger, Martin J.; Dubey, Jitender P.; Porcella, Stephen F.; Kissinger, Jessica C.; Howe, Daniel K.; Grigg, Michael E.; Parkinson, John
Title: Systems-Based Analysis of the Sarcocystis neurona Genome Identifies Pathways That Contribute to a Heteroxenous Life Cycle Document date: 2015_2_10
ID: 64mb9smi_21
Snippet: RNA-Seq data identified at least seven SRS proteins expressed in merozoites, which was confirmed by TaqMan reverse transcription-PCR (Fig. 5C) . The three most abundantly expressed SnSRS proteins were SnSRS12 (SnSAG3), SnSRS8 (SnSAG2), and SnSRS4 (SnSAG4), as has been observed previously (44) . Importantly, the SO SN1 strain did not express SnSRS10 (SnSAG1). SnSRS10 is a highly immunogenic protein and is the major surface antigen expressed on the.....
Document: RNA-Seq data identified at least seven SRS proteins expressed in merozoites, which was confirmed by TaqMan reverse transcription-PCR (Fig. 5C) . The three most abundantly expressed SnSRS proteins were SnSRS12 (SnSAG3), SnSRS8 (SnSAG2), and SnSRS4 (SnSAG4), as has been observed previously (44) . Importantly, the SO SN1 strain did not express SnSRS10 (SnSAG1). SnSRS10 is a highly immunogenic protein and is the major surface antigen expressed on the SN3 strain (45) , which explains the high number of SN3-derived expressed se- quence tags that mapped to SnSRS10, which was transcriptionally silent in this study (Fig. 5) .
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