Selected article for: "cardiovascular disease and female male"

Author: Monika Litvinukova; Carlos Talavera-Lopez; Henrike Maatz; Daniel Reichart; Catherine L. Worth; Eric L. Lindberg; Masatoshi Kanda; Krzysztof Polanski; Eirini S. Fasouli; Sara Samari; Kenny Roberts; Elizabeth Tuck; Matthias Heinig; Daniel DeLaughter; Barbara McDonough; Hiroko Wakimoto; Joshua M. Gorham; Emily Nadelmann; Krishnaa T. Mahbubani; Kourosh Saeb-Parsy; Giannino Patone; Joseph J Boyle; Hongbo Zhang; Hao Zhang; Anissa Viveiros; Gavin Oudit; Omer Bayraktar; J. G. Seidman; Christine Seidman; Michela Noseda; Norbert Hubner; Sarah A. Teichmann
Title: Cells and gene expression programs in the adult human heart
  • Document date: 2020_4_5
  • ID: 1ilforzm_9
    Snippet: The cell distributions were generally similar in tissues of male and female hearts, but left ventricular regions (AX, SP, LV) from female donors had significantly higher mean percentages of CM (46.7±12%) compared to male donors (33.9±10%; p -value=0.008). This is unexpected given the average smaller heart mass of women and may reflect the small donor pool. If replicated, these data may explain higher cardiac stroke volume in women 6 and lower r.....
    Document: The cell distributions were generally similar in tissues of male and female hearts, but left ventricular regions (AX, SP, LV) from female donors had significantly higher mean percentages of CM (46.7±12%) compared to male donors (33.9±10%; p -value=0.008). This is unexpected given the average smaller heart mass of women and may reflect the small donor pool. If replicated, these data may explain higher cardiac stroke volume in women 6 and lower rates of cardiovascular disease.

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