Author: Draz, Mohamed Shehata; Shafiee, Hadi
Title: Applications of gold nanoparticles in virus detection Document date: 2018_2_15
ID: 1xjmlwqr_111
Snippet: of the PCR amplification step and the possibility of direct and rapid detection of the target virus within a few minutes. Other assays rely on well-known analytical techniques, such as ICP-MS and QCM, which have been introduced to virus nucleic acid detection for the first time through the application of AuNPs and have achieved detection sensitivity down to femtomolar concentrations [93, 94] . Aside from these immunological and molecular assays, .....
Document: of the PCR amplification step and the possibility of direct and rapid detection of the target virus within a few minutes. Other assays rely on well-known analytical techniques, such as ICP-MS and QCM, which have been introduced to virus nucleic acid detection for the first time through the application of AuNPs and have achieved detection sensitivity down to femtomolar concentrations [93, 94] . Aside from these immunological and molecular assays, AuNPs have also been described for viral load testing by detecting intact virus particles, which are of special interest as a substitution to traditional cell culture technique [58, 65, 92] . In this context, the small size of AuNPs probes that is comparable to virus particles, allows rapid, and highly dynamic interaction with viruses for gaining information about infectivity.
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