Selected article for: "chain reaction and RT PCR chain reaction"

Author: Lingjie Song; Miao He; Xu Jia
Title: A case of SARS-CoV-2 carrier for 32 days with several times false negative nucleic acid tests
  • Document date: 2020_4_6
  • ID: lwxt4587_1
    Snippet: Since the outbreak of severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) in Wuhan (Hubei, China) in December 2019 [1] , it has spread rapidly across the globe and has become a major public health emergency worldwide. The international commission classification of viruses (ICTV) announced that 2019-nCoV was officially classified as SARS-CoV-2 [2] . The world health organization (WHO) announced that the official name of the disease.....
    Document: Since the outbreak of severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) in Wuhan (Hubei, China) in December 2019 [1] , it has spread rapidly across the globe and has become a major public health emergency worldwide. The international commission classification of viruses (ICTV) announced that 2019-nCoV was officially classified as SARS-CoV-2 [2] . The world health organization (WHO) announced that the official name of the disease caused by this virus is coronavirus disease (COVID-19) [3] . The outbreak has led the Chinese government to take drastic measures to contain the outbreak, including isolating millions of residents in Wuhan and other affected cities. According to the "Diagnosis and Treatment of COVID-19 (Trial Version 7)", the disease must be confirmed by reverse transcription polymerase chain reaction (RT-PCR) or pathogen gene sequencing from respiratory, digestive and blood samples. The RT-PCR test is often used for clinical detection. Recently, it has been reported that the patients had clinical symptoms but their nasopharyngeal swab showed negative RT-PCR results [4] . Thus, it is necessary to study the causes of these multiple RT-PCR negative results.

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