Author: William Binning; Aja E. Hogan-Cann; Diana Yae Sakae; Matthew Maksoud; Valeriy Ostapchenko; Mohammed Al-Onaizi; Sara Matovic; Wei-Yang Lu; Marco A. M. Prado; Wataru Inoue; Vania F. Prado
Title: Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice Document date: 2020_1_28
ID: ely200x3_4
Snippet: It is increasingly recognized that microglia may be neurotoxic or exert beneficial roles depending on their activation status and release of mediators (Li and Barres, 2018) . Among the multiple signals that operate on microglia to modulate their functional state and coordinate their diverse repertoire of functions are neurotransmitters. Microglia express numerous types of neurotransmitter receptors such as those for glutamate, GABA, serotonin, ad.....
Document: It is increasingly recognized that microglia may be neurotoxic or exert beneficial roles depending on their activation status and release of mediators (Li and Barres, 2018) . Among the multiple signals that operate on microglia to modulate their functional state and coordinate their diverse repertoire of functions are neurotransmitters. Microglia express numerous types of neurotransmitter receptors such as those for glutamate, GABA, serotonin, adrenaline and acetylcholine (Kettenmann et al., 2011; Li and Barres, 2018) .
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