Author: Wu, Joseph T.; Peak, Corey M.; Leung, Gabriel M.; Lipsitch, Marc
Title: Fractional Dosing of Yellow Fever Vaccine to Extend Supply: A Modeling Study Document date: 2016_11_10
ID: 02pjdufw_27
Snippet: We estimate that the vaccine coverage in Kinshasa was 20% at the end of June 2016 before the vaccination campaign began. (5) is above 0·2. That is, the WHO dose-sparing strategy is optimal as long as five-fold fractional vaccines are at least 20% efficacious. These figures are based on the assumption of a sustained epidemic such that transmission declines when the population of susceptible hosts is depleted......
Document: We estimate that the vaccine coverage in Kinshasa was 20% at the end of June 2016 before the vaccination campaign began. (5) is above 0·2. That is, the WHO dose-sparing strategy is optimal as long as five-fold fractional vaccines are at least 20% efficacious. These figures are based on the assumption of a sustained epidemic such that transmission declines when the population of susceptible hosts is depleted.
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