Author: Hur, Gyu Young; Broide, David H.
Title: Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma Document date: 2019_6_4
ID: 6j3k3viu_34
Snippet: Sex hormones may contribute to the higher prevalence and severity of adult asthma in women compared to men. As female asthmatics in their reproductive years may have perimenstrual worsening of asthma symptoms, changes in levels of hormones, such as estrogen, may contribute. Estrogen acts via the ESR1 and β. In a longitudinal study of ESR1 SNPs and lung function in 200 asthma probands and their families (males and females) with a median 20.1 year.....
Document: Sex hormones may contribute to the higher prevalence and severity of adult asthma in women compared to men. As female asthmatics in their reproductive years may have perimenstrual worsening of asthma symptoms, changes in levels of hormones, such as estrogen, may contribute. Estrogen acts via the ESR1 and β. In a longitudinal study of ESR1 SNPs and lung function in 200 asthma probands and their families (males and females) with a median 20.1 years of follow-up, 2 ESR1 SNPs (rs2077647 and rs9340799) were significantly associated with the rapid decline of FEV1 (15.7 mL/year for TT of rs2077647 and 16.1 mL/
Search related documents:
Co phrase search for related documents- adult asthma and female asthmatic: 1
- adult asthma and female male: 1
- adult asthma and follow year: 1
- adult asthma and high prevalence: 1, 2
- adult asthma and longitudinal study: 1
- adult asthma and lung function: 1, 2, 3, 4, 5, 6, 7, 8
- adult asthma and rapid decline: 1
- asthma symptom and follow year: 1
- asthma symptom and high prevalence: 1, 2
- asthma symptom and lung function: 1, 2, 3, 4, 5
- female asthmatic and lung function: 1
- female male and follow year: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- female male and high prevalence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- female male and hormone level: 1
- female male and longitudinal study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- female male and lung function: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- follow year and longitudinal study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22
- follow year and lung function: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- follow year and median follow year: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
Co phrase search for related documents, hyperlinks ordered by date