Selected article for: "powerful approach and sickness behavior"
Author: William Binning; Aja E. Hogan-Cann; Diana Yae Sakae; Matthew Maksoud; Valeriy Ostapchenko; Mohammed Al-Onaizi; Sara Matovic; Wei-Yang Lu; Marco A. M. Prado; Wataru Inoue; Vania F. Prado
Title: Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice
  • Document date: 2020_1_28
    • ID: ely200x3_116
    Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.01.27.921809 doi: bioRxiv preprint vivo can be a powerful approach to modulate microglia and regulate cytokine production and the resulting sickness behavior. This approach allows the manipulation of microglial activity in vivo and the ability to study the cross-talk between microglia and neurons in different settings, including during devel.....
    Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.01.27.921809 doi: bioRxiv preprint vivo can be a powerful approach to modulate microglia and regulate cytokine production and the resulting sickness behavior. This approach allows the manipulation of microglial activity in vivo and the ability to study the cross-talk between microglia and neurons in different settings, including during development and in mouse models of neurodegenerative diseases. Transmembrane current density (pA/pF) graph for CX3CR1CreER-hM3Dq(+/-) microglia in control conditions (baseline), and after being sequentially exposed to 3 µM CNO and 20 µM SKF-96365. author/funder. All rights reserved. No reuse allowed without permission.

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