Author: Srivastava, Sukrit; Kamthania, Mohit; Singh, Soni; Saxena, Ajay K; Sharma, Nishi
Title: Structural basis of development of multi-epitope vaccine against Middle East respiratory syndrome using in silico approach Document date: 2018_11_21
ID: 33h22ikl_4
Snippet: For vaccine development, proteins critically involved in virus-host cell interaction, viral proliferation, and host cell disruption were chosen. Thirteen proteins of MERS-CoV proteome chosen for epitope screening included the following: S glycoprotein; E protein; N protein; M protein; ORFs (ORF3, ORF4a, ORF4b, and ORF5); ORF1a (4P16), a papain-like protease (PL(pro)); ORF1a (4RSP), a protease.....
Document: For vaccine development, proteins critically involved in virus-host cell interaction, viral proliferation, and host cell disruption were chosen. Thirteen proteins of MERS-CoV proteome chosen for epitope screening included the following: S glycoprotein; E protein; N protein; M protein; ORFs (ORF3, ORF4a, ORF4b, and ORF5); ORF1a (4P16), a papain-like protease (PL(pro)); ORF1a (4RSP), a protease
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