Author: Sztuba-Solinska, Joanna; Teramoto, Tadahisa; Rausch, Jason W.; Shapiro, Bruce A.; Padmanabhan, Radhakrishnan; Le Grice, Stuart F. J.
Title: Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome Document date: 2013_3_26
ID: 1pbd4maf_24
Snippet: To examine the TL1/PK2 tertiary interaction (13, 16) , antisense-interfered SHAPE (aiSHAPE) strategy has been applied (37) . In this method, displacement of one strand of an RNA duplex by hybridizing an antisense oligonucleotide would disrupt long-distance interactions and would be characterized by enhanced NMIA sensitivity of the displaced nucleotides ( Figure 3A) ......
Document: To examine the TL1/PK2 tertiary interaction (13, 16) , antisense-interfered SHAPE (aiSHAPE) strategy has been applied (37) . In this method, displacement of one strand of an RNA duplex by hybridizing an antisense oligonucleotide would disrupt long-distance interactions and would be characterized by enhanced NMIA sensitivity of the displaced nucleotides ( Figure 3A) .
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