Selected article for: "Bundibugyo ebolavirus and Ebolavirus genus"
Author: Cross, Robert W.; Mire, Chad E.; Borisevich, Viktoriya; Geisbert, Joan B.; Fenton, Karla A.; Geisbert, Thomas W.
Title: The Domestic Ferret (Mustela putorius furo) as a Lethal Infection Model for 3 Species of Ebolavirus
  • Document date: 2016_8_15
    • ID: 6nu7rob8_1
    Snippet: Until recently, 3 members of the genus Ebolavirus-Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), and Bundibugyo ebolavirus (BEBOV)-have been responsible for small, sporadic outbreaks of Ebola hemorrhagic fever (EHF) in humans throughout Central Africa. From December 2013 through January 2016, the devastating emergence of ZEBOV in Western Africa resulted in overwhelming societal tolls in the region. The already weakened public health infrastr.....
    Document: Until recently, 3 members of the genus Ebolavirus-Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), and Bundibugyo ebolavirus (BEBOV)-have been responsible for small, sporadic outbreaks of Ebola hemorrhagic fever (EHF) in humans throughout Central Africa. From December 2013 through January 2016, the devastating emergence of ZEBOV in Western Africa resulted in overwhelming societal tolls in the region. The already weakened public health infrastructure of the region, coupled with a dearth of available, approved diagnostic assays, vaccines, or therapeutic agents, likely contributed to the severity of this epidemic. During the course of the epidemic, a number of medical countermeasures were introduced, but screening and validation of these interventions in animal models were limited by the use of host-adapted small-animal models or the availability of nonhuman primate (NHP) resources [1] .

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