Author: Pickett, Brett E.; Sadat, Eva L.; Zhang, Yun; Noronha, Jyothi M.; Squires, R. Burke; Hunt, Victoria; Liu, Mengya; Kumar, Sanjeev; Zaremba, Sam; Gu, Zhiping; Zhou, Liwei; Larson, Christopher N.; Dietrich, Jonathan; Klem, Edward B.; Scheuermann, Richard H.
Title: ViPR: an open bioinformatics database and analysis resource for virology research Document date: 2011_10_17
ID: 48ym7eti_26
Snippet: analysis tool for sequences. The metadata-driven Comparative Analysis Tool for Sequences (meta-CATS) is an automated workflow, developed by the ViPR team, to assist researchers in taking advantage of the breadth of sequence data and the accompanying metadata. Metadata is the information associated with the sequence record, including time and place of specimen isolation, host species, clinical symptoms, etc. By using statistics to simultaneously a.....
Document: analysis tool for sequences. The metadata-driven Comparative Analysis Tool for Sequences (meta-CATS) is an automated workflow, developed by the ViPR team, to assist researchers in taking advantage of the breadth of sequence data and the accompanying metadata. Metadata is the information associated with the sequence record, including time and place of specimen isolation, host species, clinical symptoms, etc. By using statistics to simultaneously analyze the sequence and metadata, genotypephenotype associations can be inferred. This tool allows users to quickly and easily select multiple sequences, align those sequences, divide them into multiple groups based on any one (or more) metadata type(s), perform automated statistical analyses on the sequences and view the results. The output from this tool has been validated using a previously published sequence set divided into two groups based on phylogenetic tree topology (32) .
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