Selected article for: "direct evidence and low certainty low evidence"

Author: Rocio Bravo Jeria; Maria X Rojas Reyes; Juan V Franco; Maria P Acuna; Luz A Torres Lopez; Gabriel rada Rada
Title: Chloroquine and hydroxychloroquine for the treatment of COVID-19: A living systematic review protocol
  • Document date: 2020_4_8
  • ID: fckn8ld4_27
    Snippet: We will preferently include randomised trials. However, information from non-randomised studies will be used if there is no direct evidence from randomised trials or the certainty of evidence for the critical outcomes resulting from the randomised trials is graded as low-or very low, and the certainty provided by the non-randomised evidence grades higher than the one provided by the randomised evidence [23] ......
    Document: We will preferently include randomised trials. However, information from non-randomised studies will be used if there is no direct evidence from randomised trials or the certainty of evidence for the critical outcomes resulting from the randomised trials is graded as low-or very low, and the certainty provided by the non-randomised evidence grades higher than the one provided by the randomised evidence [23] .

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