Author: Rocio Bravo Jeria; Maria X Rojas Reyes; Juan V Franco; Maria P Acuna; Luz A Torres Lopez; Gabriel rada Rada
Title: Chloroquine and hydroxychloroquine for the treatment of COVID-19: A living systematic review protocol Document date: 2020_4_8
ID: fckn8ld4_5
Snippet: Theory aside, the use of antimalarials attracted attention after a news briefing by the Chinese government in February 2020 revealed that, according to several Chinese studies, chloroquine and hydroxychloroquine seemed 'to have apparent efficacy and acceptable safety against COVID-19' [15] . No empirical data supporting these findings have been published so far. A second boost of attention on antimalarials came after the release of a non-randomis.....
Document: Theory aside, the use of antimalarials attracted attention after a news briefing by the Chinese government in February 2020 revealed that, according to several Chinese studies, chloroquine and hydroxychloroquine seemed 'to have apparent efficacy and acceptable safety against COVID-19' [15] . No empirical data supporting these findings have been published so far. A second boost of attention on antimalarials came after the release of a non-randomised study -with considerable methodological limitations -claiming that a combination of hydroxychloroquine and azithromycin achieved a high level of SARS-CoV-2 clearance in respiratory secretions [16] . 1 Most researchers have asked for caution while we wait for the information from dozens of randomised trials already ongoing or planned, but the US Food and Drug Administration has authorized clinicians to prescribe it for patients admitted to hospital, despite warnings from scientific advisers [17] .
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