Uterine adenocarcinoma with feline leukemia virus infection

Cho, Sung-Jin; Lee, Hyun-A; Hong, Sunhwa; Kim, Okjin

Feline endometrial adenocarcinomas are uncommon malignant neoplasms that have to date been poorly characterized. In this study, a case of uterine adenocarcinoma case is described in a Persian cat with FeLV infection. At the time of presentation, the cat was a 2-year-old female Persian chinchilla ( Figure 1A ). She presented with vaginal discharge and interrupted vomiting, and was given a health examination. Abdominal sonography and radiography demonstrated abnormal enlargement of the uterus in the abdominal cavity. The blood analysis revealed neutrophilia and lymphopenia. The concentrations of progesterone and estrogen in blood were evaluated and the results revealed normal ranges. The cat underwent surgical ovariohystectomy. During the laparotomy, thickening and inflammatory lesions of the omentum and spleen were observed ( Figure 1B ). The results of bacterial culture with omentum and spleen samples were negative for pathogenic bacteria. The ovariouterus and the omentum were removed surgically, submitted to gross examination, and trimmed. Cross-sections of the uterine wall revealed a thickening of uterine horn ( Figure 2 ). Additionally, yellowish contents were observed in the lumen of the uterus.