Selected article for: "amino acid and Codon usage"

Author: Bahir, Iris; Fromer, Menachem; Prat, Yosef; Linial, Michal
Title: Viral adaptation to host: a proteome-based analysis of codon usage and amino acid preferences
  • Document date: 2009_10_13
  • ID: 629kl04a_23
    Snippet: Next, we tested the similarity between virus, host amino acid, and codon preferences, as a measure for coherent adaptation of viruses with respect to their host taxonomical groups ( Figure 4B, right) . Interestingly, viruses that infect humans are not only adapted to the human host, but are also similar in codon preference to host groups comprising mammals excluding humans (M), and vertebrates excluding mammals (V, mostly viruses of fish and bird.....
    Document: Next, we tested the similarity between virus, host amino acid, and codon preferences, as a measure for coherent adaptation of viruses with respect to their host taxonomical groups ( Figure 4B, right) . Interestingly, viruses that infect humans are not only adapted to the human host, but are also similar in codon preference to host groups comprising mammals excluding humans (M), and vertebrates excluding mammals (V, mostly viruses of fish and birds). On the other hand, the codon usage of viruses infecting vertebrates is highly dissimilar from that of all host groups shown (the opposite of that for human viruses, Supplementary information S1).

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