Author: Liu, Justin K.H.
Title: The history of monoclonal antibody development – Progress, remaining challenges and future innovations Document date: 2014_9_11
ID: 1e4dzy64_16
Snippet: Monoclonal antibodies present an attractive option for the development of new therapies and molecular drug targets against a wide variety of common diseases due to their specificity and flexibility. Considerations when choosing the types of monoclonal antibodies to develop include: its method of production, avidity, its effector function and its delivery to its target tissue (e.g. a smaller scFv may be able to penetrate a tumour more effectively .....
Document: Monoclonal antibodies present an attractive option for the development of new therapies and molecular drug targets against a wide variety of common diseases due to their specificity and flexibility. Considerations when choosing the types of monoclonal antibodies to develop include: its method of production, avidity, its effector function and its delivery to its target tissue (e.g. a smaller scFv may be able to penetrate a tumour more effectively than a full-sized antibody). However, despite its drawbacks, there is still major interest from pharmaceutical companies to develop monoclonal antibodies for both clinical and diagnostic use and this will surely dictate the future of treatment and management of common, chronic conditions from a clinical and economical point of view.
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