Selected article for: "asthma development and lung function"
Author: Hur, Gyu Young; Broide, David H.
Title: Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma
  • Document date: 2019_6_4
    • ID: 6j3k3viu_5
    Snippet: A combination of genetic and environmental factors leads to the development of asthma. Although over 100 genes have been linked to the development of asthma, the most reproduced asthma-associated genes include IL33, IL1RL1, IL13, TSLP, HLA, GATA3, SMAD3 and genes localized to chromosome 17q12-21 (ORMDL3 and GSDMB). 8 In addition, several genes (ADAM33, PLAUR, VEGF, IL13, CHI3L1, TSLP, GSDMB, TGFB1, POSTN, ESR1 and ARG2) have been associated with .....
    Document: A combination of genetic and environmental factors leads to the development of asthma. Although over 100 genes have been linked to the development of asthma, the most reproduced asthma-associated genes include IL33, IL1RL1, IL13, TSLP, HLA, GATA3, SMAD3 and genes localized to chromosome 17q12-21 (ORMDL3 and GSDMB). 8 In addition, several genes (ADAM33, PLAUR, VEGF, IL13, CHI3L1, TSLP, GSDMB, TGFB1, POSTN, ESR1 and ARG2) have been associated with decline in lung function in asthma ( Table 1 ) and/or the features of airway remodeling (

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