Author: Andrew Rambaut; Edward C Holmes; Verity Hill; Aine OToole; John McCrone; Chris Ruis; Louis du Plessis; Oliver Pybus
Title: A dynamic nomenclature proposal for SARS-CoV-2 to assist genomic epidemiology Document date: 2020_4_19
ID: l7ymcyw7_3
Snippet: There is no universal approach to classifying virus genetic diversity below the level of a virus species. Typically, genetic diversity is categorised into distinct 'clades', each of which corresponds to a monophyletic group on a phylogenetic tree. These clades may be referred to by a variety of terms, such as 'subtypes', 'genotypes', 'groups', depending on the taxonomic level under investigation or the established scientific literature for the vi.....
Document: There is no universal approach to classifying virus genetic diversity below the level of a virus species. Typically, genetic diversity is categorised into distinct 'clades', each of which corresponds to a monophyletic group on a phylogenetic tree. These clades may be referred to by a variety of terms, such as 'subtypes', 'genotypes', 'groups', depending on the taxonomic level under investigation or the established scientific literature for the virus in question. The clades usually reflect an attempt to divide pathogen phylogeny and genetic diversity into a set of groupings that are approximately equally divergent, mutually exclusive and statistically well supported. All genome sequences are therefore allocated to one clade or provisionally labelled as unclassified. Often multiple hierarchical levels of classification exist for the same pathogens, such as the terms 'type', 'group' and 'subtype' that are used in the field of HIV research.
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