Author: Hayward, Gail; Thompson, Matthew; Heneghan, Carl; Perera, Rafael; Del Mar, Chris; Glasziou, Paul
Title: Corticosteroids for pain relief in sore throat: systematic review and meta-analysis Document date: 2009_8_6
ID: 67bhdlzy_35
Snippet: Our findings suggest that in patients with severe or exudative sore throat, pain can be reduced and resolution hastened by use of corticosteroids in conjunction with antibiotic therapy. Current UK practice is to assess the likelihood of group A streptococcus infection using the Centor criteria22 (tender lymphadenopathy, exudate, fever, absence of cough). Our research suggests that patients with severe or high Centor scoring sore throat would bene.....
Document: Our findings suggest that in patients with severe or exudative sore throat, pain can be reduced and resolution hastened by use of corticosteroids in conjunction with antibiotic therapy. Current UK practice is to assess the likelihood of group A streptococcus infection using the Centor criteria22 (tender lymphadenopathy, exudate, fever, absence of cough). Our research suggests that patients with severe or high Centor scoring sore throat would benefit from a single dose of corticosteroids. The use of corticosteroids will triple the likelihood of resolution at 24 hours and hasten this resolution by more than 6 hours, even in patients who have also been given antibiotics and analgesics.
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