Selected article for: "intensive care and respiratory failure"
Author: Nicastri, Emanuele; Petrosillo, Nicola; Bartoli, Tommaso Ascoli; Lepore, Luciana; Mondi, Annalisa; Palmieri, Fabrizio; D’Offizi, Gianpiero; Marchioni, Luisa; Murachelli, Silvia; Ippolito, Giuseppe; Antinori, Andrea
Title: National Institute for the Infectious Diseases “L. Spallanzani”, IRCCS. Recommendations for COVID-19 clinical management
  • Document date: 2020_3_16
    • ID: 4r0t3q7j_54
    Snippet: TCZ is a potential treatment strategy in severe and critical COVID-19 patients. In particular, patients who could benefit from TCZ therapy are: 1) Patients with respiratory symptoms, unstable and severe but not in critical conditions (e.g. clinical instability score of MEWS 3-4) with evidence of worsening of gas exchange with mild to moderate dyspnoea, tachypnea, worsening of SpO2 or arterial blood gas analysis parameters in ambient air (SpO2 ≤.....
    Document: TCZ is a potential treatment strategy in severe and critical COVID-19 patients. In particular, patients who could benefit from TCZ therapy are: 1) Patients with respiratory symptoms, unstable and severe but not in critical conditions (e.g. clinical instability score of MEWS 3-4) with evidence of worsening of gas exchange with mild to moderate dyspnoea, tachypnea, worsening of SpO2 or arterial blood gas analysis parameters in ambient air (SpO2 ≤ 93% in ambient air, PaO2/FiO2 ≤ 300 mmHg) in the absence of critical manifestations or signs of alarm (severe respiratory failure, respiratory distress, altered state of consciousness, hypotension, cardiovascular shock); 2) Patient with respiratory symptoms in critical conditions (e.g. clinical instability score of MEWS > 4) with evidence of ARDS (from moderate ARDS according to the Berlin definition: 100 mmHg
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