Author: Groeneveld, Geert H; van der Reyden, Tanny J; Joosten, Simone A; Bootsma, Hester J; Cobbaert, Christa M; de Vries, Jutte J C; Kuijper, Ed J; van Dissel, Jaap T
Title: Non-lytic antibiotic treatment in community-acquired pneumococcal pneumonia does not attenuate inflammation: the PRISTINE trial Document date: 2019_5_18
ID: 19ueli6e_32
Snippet: Following our hypothesis, LTA release and biomarker response after the start of treatment was assumed to not have a linear relationship. Therefore, we used polynomial splines to model the trend of LTA release and biomarker response. Changes in biomarkers were assessed by comparing changes within the first and second 24 h after treatment with a Student's t-test. Statistical analyses were performed using SPSS (IBM Software) version 23......
Document: Following our hypothesis, LTA release and biomarker response after the start of treatment was assumed to not have a linear relationship. Therefore, we used polynomial splines to model the trend of LTA release and biomarker response. Changes in biomarkers were assessed by comparing changes within the first and second 24 h after treatment with a Student's t-test. Statistical analyses were performed using SPSS (IBM Software) version 23.
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