Pathology of infectious diseases: new agents, opportunistic, neglectable, emergent, reemergent diseases and why not super resistant nosocomial bacteria?

Duarte-Neto, Amaro Nunes

are networks, where specialists from different regions of the world can be connected to exchange knowledge. 25 The H&E stained slide (A) shows numerous necrotic hepatocytes and some (arrows) with typical Cowdry type A inclusion (nuclei with ground glass appearance and multinucleated cells with nuclear molding and peripheral margination of chromatin). The electron microscopy (B) shows HSV1 virions, measuring up to 0,1 µm, in liver capillaries, near to red cells (arrows), as the infection is systemic; C, D -Congenital cytomegaloviruses. The H&E stained slide (C) shows renal tubular cells with the typical CMV inclusion-the owl´s eye (arrow), with cytomegaly, eosinophilic nuclear inclusion, surrounded by clear halo and granular cytoplasmic inclusions. (D) the electron microscopy shows numerous virions grouped in the nucleus (arrows), some budding from the nuclear membrane to complete its cycle in the cytoplasm (small arrow). Magnification. A, C -400x, B, D -40,000x.