Author: Yan, Xiujuan; Li, Yingxiu; Choi, Yun Ho; Wang, Chongyang; Piao, Yihua; Ye, Jing; Jiang, Jingzhi; Li, Liangchang; Xu, Huixian; Cui, Qingsong; Yan, Guanghai; Jin, Minggen
Title: Protective Effect and Mechanism of Alprostadil in Acute Respiratory Distress Syndrome Induced by Oleic Acid in Rats Document date: 2018_10_8
ID: 7ea7ur3b_7
Snippet: In this study, an OA-induced ARDS model was used to investigate the effects of alprostadil on lung injury. Moreover, the possible mechanisms involved in alprostadil's role in ARDS were also examined in MAPKs and NF-kB pathways, ACE expression, and apoptosis. Our study thus may provide experimental evidence for the clinical use of alprostadil for treatment of ARDS......
Document: In this study, an OA-induced ARDS model was used to investigate the effects of alprostadil on lung injury. Moreover, the possible mechanisms involved in alprostadil's role in ARDS were also examined in MAPKs and NF-kB pathways, ACE expression, and apoptosis. Our study thus may provide experimental evidence for the clinical use of alprostadil for treatment of ARDS.
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