Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus

Munday, Diane C.; Emmott, Edward; Surtees, Rebecca; Lardeau, Charles-Hugues; Wu, Weining; Duprex, W. Paul; Dove, Brian K.; Barr, John N.; Hiscox, Julian A.

Data sets of identified and both identified and quantified cellular and viral proteins in the nuclear and cytoplasmic fractions are presented in supplemental Tables 1-7. Here, information is included such as the protein identification in the International Protein Index format, the abundance as a ratio of HRSV/mock, the UniProt identification, number of peptides used to identify the protein, the sequence coverage this represents, predicted protein details such as molecular weight and length, the gel slice in which this protein was present, and the PEP score. Note that for the ratio of HRSV/mock a score of 0.5 or lower indicates a 2-fold or greater decrease in abundance in HRSV-infected cells and that a score of 2 or more indicates a 2-fold or greater increase in abundance in HRSV-infected cells in the appropriate fraction.