Author: Lundegaard, Claus; Lund, Ole; Kesmir, Can; Brunak, Søren; Nielsen, Morten
Title: Modeling the adaptive immune system: predictions and simulations Document date: 2007_12_15
ID: 5m269nzi_17
Snippet: When comparing different methods, the thresholdindependent measures are to be preferred. Otherwise a threshold has to be set under the same assumptions for all predictors. As an example one can estimate the specificity for each predictor by setting the threshold for the given predictor to a value where the sensitivity will be 0.5 (i.e. half of the total available positives is over the threshold), or estimate the sensitivity at a threshold where t.....
Document: When comparing different methods, the thresholdindependent measures are to be preferred. Otherwise a threshold has to be set under the same assumptions for all predictors. As an example one can estimate the specificity for each predictor by setting the threshold for the given predictor to a value where the sensitivity will be 0.5 (i.e. half of the total available positives is over the threshold), or estimate the sensitivity at a threshold where the specificity will be 0.8 (i.e. 80% of the AN are predicted as negatives).
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