Title: Triggering through CD16 or phorbol esters enhances adhesion of NK cells to laminin via very late antigen 6 Document date: 1992_11_1
ID: 3ymo8zw0_31
Snippet: Overall, our results suggest that expression of VLA-6 on NK cells appears to be particularly relevant for their migration, tissue localization, and functions . VLA-6-mediated NK cell adhesion to LM is likely to be critical for migration through basement membranes where LM is a major constituent . In this regard, LM has been found to facilitate NK cell migration in response to several chemotactic stimuli (30) . The activation-dependent increase in.....
Document: Overall, our results suggest that expression of VLA-6 on NK cells appears to be particularly relevant for their migration, tissue localization, and functions . VLA-6-mediated NK cell adhesion to LM is likely to be critical for migration through basement membranes where LM is a major constituent . In this regard, LM has been found to facilitate NK cell migration in response to several chemotactic stimuli (30) . The activation-dependent increase in VLA-6-mediated NK cell adhesion to LM may be relevant to temporarily immobilize NK cells at the site of ongoing inflammatory or immune responses, and prevent them from escaping into the circulation .
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