Selected article for: "SFVT component and variant type feature"
Author: Pickett, Brett E.; Sadat, Eva L.; Zhang, Yun; Noronha, Jyothi M.; Squires, R. Burke; Hunt, Victoria; Liu, Mengya; Kumar, Sanjeev; Zaremba, Sam; Gu, Zhiping; Zhou, Liwei; Larson, Christopher N.; Dietrich, Jonathan; Klem, Edward B.; Scheuermann, Richard H.
Title: ViPR: an open bioinformatics database and analysis resource for virology research
  • Document date: 2011_10_17
    • ID: 48ym7eti_12
    Snippet: We have recently developed a novel Sequence Feature Variant Type (SFVT) component in ViPR that catalogs the precise location of characterized regions within virus proteins. This component is based on similar work performed for the human HLA proteins (17) , and has been customized for the virology community. Information used to define the various 'Sequence Features' (SFs) was obtained from UniProt, GenBank, IEDB and the scientific literature. SFs .....
    Document: We have recently developed a novel Sequence Feature Variant Type (SFVT) component in ViPR that catalogs the precise location of characterized regions within virus proteins. This component is based on similar work performed for the human HLA proteins (17) , and has been customized for the virology community. Information used to define the various 'Sequence Features' (SFs) was obtained from UniProt, GenBank, IEDB and the scientific literature. SFs are categorized as structural (e.g. alpha helices), functional (e.g. active sites), immune epitopes and sequence alteration positions, with current support for Hepatitis C (subtype 1a), Dengue (serotypes 1-4) and Pox (Vaccinia) viruses. Initial SF definitions for each characterized region have been inspected and validated by domain experts to ensure accuracy.

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