Selected article for: "Codon adaptation and different codon"
Author: Bahir, Iris; Fromer, Menachem; Prat, Yosef; Linial, Michal
Title: Viral adaptation to host: a proteome-based analysis of codon usage and amino acid preferences
  • Document date: 2009_10_13
    • ID: 629kl04a_4
    Snippet: Viruses do not have tRNAs, and consequently the translation of viral proteins relies entirely on the pool of host tRNAs. An exception is the Paramecium bursaria chlorella virus, which contains a partial set of tRNAs and other host-like properties (Van Etten and Meints, 1999) . In a recent study that tested the codon usage adaptation for over 100 bacteriophages infecting 10 different bacterial hosts, it was shown that the bacteriophage genomes are.....
    Document: Viruses do not have tRNAs, and consequently the translation of viral proteins relies entirely on the pool of host tRNAs. An exception is the Paramecium bursaria chlorella virus, which contains a partial set of tRNAs and other host-like properties (Van Etten and Meints, 1999) . In a recent study that tested the codon usage adaptation for over 100 bacteriophages infecting 10 different bacterial hosts, it was shown that the bacteriophage genomes are under codon-selective pressure imposed by the translational biases of their respective hosts (Carbone, 2008) . The reasoning underlying this codon selection hypothesis argues that it provides an advantage for viral protein synthesis at the level of translational efficiency.

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