Author: Hölzer, Martin; Schoen, Andreas; Wulle, Julia; Müller, Marcel A.; Drosten, Christian; Marz, Manja; Weber, Friedemann
Title: Virus- and Interferon Alpha-Induced Transcriptomes of Cells from the Microbat Myotis daubentonii Document date: 2019_8_10
ID: 0co6m9af_17
Snippet: At 24 h, the number of upregulated genes was decreased to 106, of which 1 gene (PLA1A) was actually unique for this late time point. Moreover For the IFN-stimulated transcriptomes, predominant biological processes both at 6 and 24 h post infection encompassed antigen processing and presentation, antiviral defense, immune response, and NF-kB regulation ( Figure S4B ). Additionally, at 6 h there are indications of both up-and downregulation of intr.....
Document: At 24 h, the number of upregulated genes was decreased to 106, of which 1 gene (PLA1A) was actually unique for this late time point. Moreover For the IFN-stimulated transcriptomes, predominant biological processes both at 6 and 24 h post infection encompassed antigen processing and presentation, antiviral defense, immune response, and NF-kB regulation ( Figure S4B ). Additionally, at 6 h there are indications of both up-and downregulation of intracellular and transmembrane transport, and at 24 h oxidoreductase activity is mostly downregulated.
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