Author: Zhang, Qingyu; Liu, Lihua; Sun, Wei; Gao, Fuqiang; Cheng, Liming; Li, Zirong
Title: Extracorporeal shockwave therapy in osteonecrosis of femoral head: A systematic review of now available clinical evidences Document date: 2017_1_27
ID: 4t5bjbtu_24
Snippet: In 2008, Wang et al [17] published a article included 14 patients involving 14 diseased hips graded as ARCO stage III or IV, all of which underwent THA. 7 cases also received ESWT before surgery and others were regarded as control group. ESWT group revealed more live bone and less necrotic bone as well as higher cell concentration and activity compared with control group. Factors for angiogenesis such as von Willebrand factor (vWF), CD31, vascula.....
Document: In 2008, Wang et al [17] published a article included 14 patients involving 14 diseased hips graded as ARCO stage III or IV, all of which underwent THA. 7 cases also received ESWT before surgery and others were regarded as control group. ESWT group revealed more live bone and less necrotic bone as well as higher cell concentration and activity compared with control group. Factors for angiogenesis such as von Willebrand factor (vWF), CD31, vascular cell adhesion molecule (VCAM) as well as for bone remodeling and regeneration such as Winless 3a (Wnt 3), Dickkopf-1 (DKK1) and proliferation cell nuclear antigen (PCNA) also had significant differences between ESWT group and control group. These findings prompted the regeneration effects of ESWT to ONFH.
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