Author: William Binning; Aja E. Hogan-Cann; Diana Yae Sakae; Matthew Maksoud; Valeriy Ostapchenko; Mohammed Al-Onaizi; Sara Matovic; Wei-Yang Lu; Marco A. M. Prado; Wataru Inoue; Vania F. Prado
Title: Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice Document date: 2020_1_28
ID: ely200x3_112
Snippet: It is important to note that neither chronic nor acute activation of hM3Dq in microglia affected normal mouse behavior, indicating that hM3Dq activation per se does not lead to sickness behavior or other deleterious effects. Thus, these results suggest that chemogenetics can be a powerful approach to modulate microglia and modify neuroinflammation......
Document: It is important to note that neither chronic nor acute activation of hM3Dq in microglia affected normal mouse behavior, indicating that hM3Dq activation per se does not lead to sickness behavior or other deleterious effects. Thus, these results suggest that chemogenetics can be a powerful approach to modulate microglia and modify neuroinflammation.
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