Title: The rubella virus E1 glycoprotein is arrested in a novel post-ER, pre- Golgi compartment Document date: 1992_8_2
ID: 04455ffs_63
Snippet: We assume that the elaborate smooth membrane structures found in CHOE1 cells do not represent an aberrant response of a single cell type to transfection because stably transfected BHK-21 and murine fibrosarcoma cell lines expressing E1 contained comparable structures by indirect immunofluorescence (unpublished observations). Also, these structures are not formed simply as a consequence of overexpression of membrane proteins, because they were not.....
Document: We assume that the elaborate smooth membrane structures found in CHOE1 cells do not represent an aberrant response of a single cell type to transfection because stably transfected BHK-21 and murine fibrosarcoma cell lines expressing E1 contained comparable structures by indirect immunofluorescence (unpublished observations). Also, these structures are not formed simply as a consequence of overexpression of membrane proteins, because they were not found in cells expressing both E2 and E1 or E2 alone or cells expressing other Togavirus E1 giycoproteins (26, 36, 37) .
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