Title: The v-sis oncoprotein loses transforming activity when targeted to the early Golgi complex Document date: 1994_12_2
ID: 2otgb2w8_25
Snippet: proteins constructed for these experiments. The first three constructs, sis-G, sis-G-ER +, and sisG-ER-, were described previously , and served as a basic model for the construction of these new fusion proteins. In all cases, the first 239 amino acids of v-sis are included in the fusion proteins. This portion of v-sis provides a signal sequence, a dibasic proteolytic processing site, and the 82-amino acid minimal transforming region (Hannink and .....
Document: proteins constructed for these experiments. The first three constructs, sis-G, sis-G-ER +, and sisG-ER-, were described previously , and served as a basic model for the construction of these new fusion proteins. In all cases, the first 239 amino acids of v-sis are included in the fusion proteins. This portion of v-sis provides a signal sequence, a dibasic proteolytic processing site, and the 82-amino acid minimal transforming region (Hannink and Donoghue, 1986b; Sauer et al., 1986; Giese et al., 1987; Sauer and Donoghue, 1988) . All constructs are in Type I orientation-the NH2 terminus is "out; and the COOH terminus "in"
Search related documents:
Co phrase search for related documents- amino acid and dibasic proteolytic processing site: 1
- amino acid and fusion protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- amino acid and NH2 terminus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- amino acid and previously describe: 1, 2, 3
- amino acid and processing site: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- amino acid and proteolytic processing site: 1, 2, 3, 4
- amino acid and signal sequence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- basic model and fusion protein: 1
- basic model and previously describe: 1
- COOH terminus and fusion protein: 1, 2, 3
- COOH terminus and NH2 terminus: 1, 2, 3, 4, 5, 6, 7, 8, 9
- COOH terminus and signal sequence: 1, 2, 3, 4, 5, 6, 7
- dibasic proteolytic processing site and processing site: 1
- dibasic proteolytic processing site and proteolytic processing site: 1
- dibasic proteolytic processing site and signal sequence: 1
- experiment construct and signal sequence: 1
- fusion protein and processing site: 1, 2, 3, 4, 5, 6
- fusion protein and proteolytic processing site: 1
- fusion protein and signal sequence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
Co phrase search for related documents, hyperlinks ordered by date