Author: William Binning; Aja E. Hogan-Cann; Diana Yae Sakae; Matthew Maksoud; Valeriy Ostapchenko; Mohammed Al-Onaizi; Sara Matovic; Wei-Yang Lu; Marco A. M. Prado; Wataru Inoue; Vania F. Prado
Title: Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice Document date: 2020_1_28
ID: ely200x3_61
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.01.27.921809 doi: bioRxiv preprint holed cylinder, allowing for olfactory investigation. Time of investigation was defined as the time a mouse spent sniffing through the holes of the cylinder and was manually recorded by an investigator blind to treatment. The task consisted of five trials, each 5 min long and separated with 15 min intertria.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.01.27.921809 doi: bioRxiv preprint holed cylinder, allowing for olfactory investigation. Time of investigation was defined as the time a mouse spent sniffing through the holes of the cylinder and was manually recorded by an investigator blind to treatment. The task consisted of five trials, each 5 min long and separated with 15 min intertrial intervals. The same juvenile intruder was used for the first four trials and a new juvenile intruder was introduced in trial five to assess social memory. Time spent investigating the juvenile intruder during each of the 5 trials was compared using repeated measures two-way ANOVA with multiple comparisons with Bonferroni post hoc analysis.
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