Author: Cho, Sung-Jin; Lee, Hyun-A; Hong, Sunhwa; Kim, Okjin
Title: Uterine adenocarcinoma with feline leukemia virus infection Document date: 2011_12_19
ID: 3keht8ge_7
Snippet: FeLV is an exogenous retrovirus causing several diseases in domestic cats, including tumors of most hematopoietic cells, aplastic anemia, myeloproliferative disorders, and immunosuppression [27] . The FeLVs that primarily cause Tcell tumors in cats are transmitted in a horizontal manner [28] , particularly through saliva [29] . The T-cell tropism of these agents is observed even when the virus infects human cells [30] . Although many free-roaming.....
Document: FeLV is an exogenous retrovirus causing several diseases in domestic cats, including tumors of most hematopoietic cells, aplastic anemia, myeloproliferative disorders, and immunosuppression [27] . The FeLVs that primarily cause Tcell tumors in cats are transmitted in a horizontal manner [28] , particularly through saliva [29] . The T-cell tropism of these agents is observed even when the virus infects human cells [30] . Although many free-roaming cats become persistently infected with FeLV, only a small fraction develops leukemia or lymphoma. A large number develop lethal opportunistic infections, particularly coronavirus-induced peritonitis [31] . FeLV causes lymphopenia, depressed cellmediated immune responses, thymic atrophy, and depressed humoral responses to T-cell dependent antigens despite the presence of hypergammaglobulinemia [31] .
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