Author: Wang, Ziqiang; Zhao, Yiwan; Zhang, Yaou
Title: Viral lncRNA: A regulatory molecule for controlling virus life cycle Document date: 2017_3_23
ID: 213ddk0s_15
Snippet: Viral transformation most commonly refers to the virus-induced malignant transformation of an animal cell in a body or cell culture and can impose characteristically determinable features upon a cell. Typical phenotypic changes include a high saturation density, anchorage-independent growth, loss of contact inhibition, loss of orientated growth, immortalization, and disruption of the cell's cytoskeleton, which are favorable for the viral life cyc.....
Document: Viral transformation most commonly refers to the virus-induced malignant transformation of an animal cell in a body or cell culture and can impose characteristically determinable features upon a cell. Typical phenotypic changes include a high saturation density, anchorage-independent growth, loss of contact inhibition, loss of orientated growth, immortalization, and disruption of the cell's cytoskeleton, which are favorable for the viral life cycle. Currently, viruses drive cellular transformation through their ability to alter cellular gene expression, signaling pathways, and the cell cycle [38] .
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