Selected article for: "cell line and RNA seq"
Author: Hölzer, Martin; Schoen, Andreas; Wulle, Julia; Müller, Marcel A.; Drosten, Christian; Marz, Manja; Weber, Friedemann
Title: Virus- and Interferon Alpha-Induced Transcriptomes of Cells from the Microbat Myotis daubentonii
  • Document date: 2019_8_10
    • ID: 0co6m9af_33
    Snippet: iScience 19, 647-661, September 27, 2019 657 IL17RC, OTOGL, SLC24A1) and confirm a set of ISGs as being conserved also in Yangochiroptera. Also, in contrast to findings in megabat cells, we could not detect an increased copy number or upregulation of type I IFN genes other than IFNB1, or unusually high base levels of IFNs. Moreover, based on true biological replicates we offer statistically robust RNA-seq data on a time-resolved comparison betwee.....
    Document: iScience 19, 647-661, September 27, 2019 657 IL17RC, OTOGL, SLC24A1) and confirm a set of ISGs as being conserved also in Yangochiroptera. Also, in contrast to findings in megabat cells, we could not detect an increased copy number or upregulation of type I IFN genes other than IFNB1, or unusually high base levels of IFNs. Moreover, based on true biological replicates we offer statistically robust RNA-seq data on a time-resolved comparison between virus-induced and IFN-stimulated transcriptional responses of an IFN competent mammalian cell line.

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