Selected article for: "human health and positive strand"
Author: Swatek, Kirby N.; Aumayr, Martina; Pruneda, Jonathan N.; Visser, Linda J.; Berryman, Stephen; Kueck, Anja F.; Geurink, Paul P.; Ovaa, Huib; van Kuppeveld, Frank J. M.; Tuthill, Tobias J.; Skern, Tim; Komander, David
Title: Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies
  • Document date: 2018_3_6
    • ID: 3s86w4iw_2
    Snippet: ubiquitin | ISG15 | viral signaling | FMDV | structure P icornaviruses are nonenveloped, positive-strand RNA viruses that comprise small genomes but represent significant threats to human and animal health (1) . For example, foot-and-mouth disease virus (FMDV) is a global, highly infectious animal pathogen that causes annual economic losses in livestock farming estimated between $6.5 and $21 billion US dollars (2) . Infected cattle develop fever .....
    Document: ubiquitin | ISG15 | viral signaling | FMDV | structure P icornaviruses are nonenveloped, positive-strand RNA viruses that comprise small genomes but represent significant threats to human and animal health (1) . For example, foot-and-mouth disease virus (FMDV) is a global, highly infectious animal pathogen that causes annual economic losses in livestock farming estimated between $6.5 and $21 billion US dollars (2) . Infected cattle develop fever and vesicular lesions in their mouths and hooves; consequently, FMDV outbreaks lead to culling of entire herds in FMDV-free countries to prevent the spread of the virus (3) .

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